Moderna is developing eight other vaccines using mRNA. The company has tested them in animals and in 1,700 people, and has not had any cases of anaphylaxis or other serious allergic reactions related to the vaccine, said Dr Jacqueline Miller of Moderna. A case of anaphylaxis occurred two months after vaccination in a person allergic to soy. Anaphylactic reactions to vaccines usually occur within minutes or even seconds after the injection is given.
Other side effects – fever, chills, fatigue, headache, muscle and joint pain – are much more common after receiving the Moderna vaccine, especially after the second vaccine. Although the reported side effects are not dangerous, they can be unpleasant and last for one to three days. Doctors say the symptoms are comparable to those experienced by many people after receiving Shingrix, the shingles vaccine. People should be prepared to feel under the weather for a day or two after each stroke, they said, and may need to take the day off.
Moderna’s study found that 91.6% of recipients had arm pain, 68.5% fatigue, 63% headache, 59.6% muscle pain, 44.8% joint pain and 43.4% of chills. Some participants also had swollen lymph nodes in the armpit on the side where they received the injection.
Company scientists stressed Thursday that the vaccine does not alter a person’s genes or interact with DNA, and that mRNA breaks down quickly and does not persist for long in the body.
The Moderna and Pfizer-BioNTech studies reported a small number of cases of temporary facial palsy called Bell’s palsy. Moderna found three cases in the vaccine group and one in the placebo group, and Pfizer had four, all in the vaccine group. FDA reviewers did not believe the disorder was related to the vaccine. Moderna on Thursday said the company would be monitoring the disease.
Shipment of the vaccine will be handled by the Trump administration’s Operation Warp Speed, but each state will decide where its doses go. Tennessee, for example, plans to disperse most of its planned allocation of 115,000 initial doses next week among 195 of its local health departments, which will vaccinate first responders, and in every hospital in the state that does not. did not receive a Pfizer shipment this week. .
In Kentucky, Gov. Andy Beshear told reporters he expected nearly 80,000 doses of Moderna vaccine in the state’s initial shipment, adding, “We’re going to make sure we have an allowance for. every acute care hospital in the Commonwealth. “